Glycans in Diseases and Therapeutics
Springer; 1st Edition | May 5, 2011 | ISBN-10: 3642168329 | 199 pages | PDF | 2.1 Mb
Initially believed to exist inactive molecules, glycans are now considered necessary for life, both under normal and pathological conditions. This volume of the series "Biology of Extracellular Matrix" reviews the greatest in quantity recent findings on the role of glycans in the progression in a continuously ascending gradation of diseases and the possible therapeutic use of this class of molecules. It shows for what reason the interaction of glycans with germination factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and tenacious proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic trunk cell biology. Furthermore, an extensive retrospect about the structure and pharmacological movables of unique marine glycosaminoglycans is discussed since well as the possibility of using these glycans taken in the character of therapeutic agents.
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